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REFLECTIONS
Hypertension
Hypertension Global Newsletter #8 2025
SPECIAL POPULATION Hypertension
12. Combination blood pressure lowering therapy in patients with type 2 diabetes: messages from the ADVANCE trial
Hypertension. Wang N, et al. J Hypertens. 2024 Dec 1;42(12):2055-2064. doi: 10.1097/HJH.0000000000003855. Epub
2024 Oct
13. Blood Pressure-Lowering Medications, Sodium Reduction, and Blood Pressure Hypertension. Song J, et al.
Hypertension. 2024 Nov;81(11):e149-e160. doi: 10.1161/HYPERTENSIONAHA.124.23382. Epub 2024 Sep 5.
Abbreviations
ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BB, beta-blockers; BP, blood pressure; CCB,
calcium channel blocker; CI, confidence interval; CV, cardiovascular; CVD, cardiovascular disease; DBP, diastolic blood pressure;
ESH, European Society of Hypertension; FEC, free equivalent combination; GLP-1 RA, glucagon-like peptide-1 receptor agonist;
HF, heart failure; HR, hazard ratio; IDI, integrated discrimination improvement; MACE, major adverse cardiovascular events; MRA,
mineralocorticoid receptor antagonists; NHIF, national health insurance fund; NRI, net reclassification improvement; PDC, proportion
of days covered; R/A, ramipril/amlodipine; RCT, randomised controlled trial; SBP, systolic blood pressure; SD, standard deviation;
SPC, single-pill combination; T2D, type 2 diabetes; T2DM, type 2 diabetes mellitus; TTR, time in target range.
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