Page 11 - hypertension_newsletter8

REFLECTIONS
Hypertension
Hypertension Global Newsletter #8 2025

Hypertension

The authors found that in patients with T2D and an elevated SBP,
the incidence of major CVD events for up to five years of follow- CLINICAL PEARLS FROM THE FACULTY
up was significantly lower with an intensive treatment strategy to
lower SBP to less than 120 mmHg than with a standard treatment
strategy to lower SBP to less than 140 mmHg, with a hazard ratio
of 0.79 (95% CI, 0.69 to 0.90). The effects of the intervention were
consistent across all prespecified subgroups.

This finding is crucial as previous evidence regarding effective
SBP reduction targets in patients with T2D was inconclusive.
Earlier guidelines were influenced by the Action to Control
Cardiovascular Risk in Diabetes (ACCORD) trial and suggested
less aggressive targets. This study aligns with more recent WATCH
recommendations advocating for lower blood pressure in VIEW COMMENTARY FROM PROF.
diabetic patients. However, the study also highlights the need for CAMARGO ON THE CLINICAL
ongoing monitoring for hypotension and hyperkalaemia following RELEVANCE OF THE ARTICLE.
initiation of intensive blood pressure-lowering regimens.

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