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REFLECTIONS
Hypertension Global Newsletter #8 2025
TABLE OF CONTENTS
KEY ARTICLES
BLOOD PRESSURE TARGET
Systolic blood pressure time in target range
within 24 hours and incident heart failure:
insights from the real-world setting Tian X, et al.
Hypertens Res. 2025 Jan;48(1):223-232.
TREATMENT
Effect of single-pill versus free equivalent
combinations on persistence and major adverse
cardiovascular events in hypertension: a real-
world analysis Simonyi G, et al. J Hypertens. 2025
Mar 1;43(3):405-412.
Efficacy and safety of a novel low-dose
triple single-pill combination of telmisartan,
amlodipine and indapamide, compared with dual
combinations for treatment of hypertension:
a randomised, double-blind, active-controlled,
international clinical trial. Rodgers A, et al. Lancet.
2024 Oct 18:404(10462):1536-1546
SPECIAL POPULATIONS
Twelve hot questions in the management
of hypertension in patients aged 80+ years
and their answers with the help of the
2023 European Society of Hypertension
Guidelines Bahat G, et al. J Hypertens. 2024 Nov
1;42(11):1837-1847.
Intensive Blood-Pressure Control in Patients
with Type 2 Diabetes Bi Y, et al. N Engl J Med.
2024 Nov 16. doi: 10.1056/NEJMoa2412006.
Online ahead of print.
Effects of glucagon-like peptide-1 receptor
agonists on blood pressure in overweight or
obese patients: a meta-analysis of randomized
controlled trials Wong HJ, et al. J Hypertens. 2025
Feb 1;43(2):290-300.
ADDITIONAL ARTICLES OF INTEREST
Hypertension
Welcome back to the REFLECTIONS Hypertension
Global Newsletter series, which draws on the expertise of
international physicians to summarise the latest clinical and
real-world evidence in the field of hypertension and reflect
Hypertension
on the clinical impact of these new data on the management
of patients with hypertension. Since our last newsletter, there
have been many new and interesting publications in the
active field of clinical research in hypertension; therefore,
the Scientific Planning Committee (SPC) chose from an
extensive list of articles from high-quality scientific journals.
To make this final selection, we prioritised novel findings
over confirmatory papers and articles directly applying to
antihypertensive treatment in routine clinical practice. In
this newsletter, we will focus on 1) blood pressure targets,
2) single-pill combination treatments, and 3) special
populations, including older patients, those with diabetes,
and those with obesity. As with previous newsletters, we
invite you to engage through links to commentary videos
from authors of the publications, view short video clinical
perspectives from our SPC, and delve into the articles
through hyperlinks for in-depth study.
Prof. Laurent (Chair)
SCIENTIFIC PLANNING COMMITTEE
Prof. Stéphane Laurent Prof. Diego Araiza
(France) (Mexico)
Prof. Adriana Camargo Dr. Om Narayan
(Brazil)
(Australia)
Prof. Nqoba Tsabedze Dr. Michal Fikrle
(South Africa) (Czech Republic)